PUERARIA MIRIFICA TEST FINDS NO CANCER
Author: Anchalee Saechin
PUERARIA MIRIFICA
TEST FINDS NO CANCER
Doctor Phaichit Warachit, the
Director-General of Medical Sciences, said in
a disclosure that the Ministry of Public Health,
represented by the Department of Medical Sciences,
had conducted a preliminary study of the toxicity
of medicinal herb Pueraria mirifica the past
period of seven months for consumer protection.
The study in the first phase had now been completed,
which was a study in white mice of both sexes
by giving oral Pueraria mirifica powder at 1,000
milligrams per 1 kilogram of the mouse weight
for 3 successive months compared with the control
group receiving water.
As the outcome of the study
it was found that the dose of 10 mg/kg/day of
Pueraria mirifica did not bring about an irregularity
of blood cells of various kinds and chemicals
in blood, including not bringing about an irregularity
of the internal organs, while the mice receiving
the dose of 100 mg/kg/day of Pueraria mirifica
had a decline in growth and eating; no irregularity
of blood cells of various kinds was found, but
the protein content in the male mice decreased,
while in the female mice the uterus was found
having a increasing weight, but no irregularity
of the uterine cells was found.
Meanwhile, the dose of 1,000
mg/kg/day of Pueraria mirifica caused the growth
and eating of the mice to decrease; the number
of red corpuscles decreased in the mice of both
sexes. In the male mice there was a decrease
of one-third in white corpuscles and granules;
there was blood congestion at the testicles
while in the female mice it caused the uterus
to have and increasing weight. but no irregularity
of the uterine cells different from the control
group was found.
The above study outcome points
out that the dose of 10 mg/kg/day of Pueraria
mirifica does not cause toxicity to arise in
the experimental animals, while the dose of
100 mg/kg/day generates some irregularities
in the white mice, so the Department of medical
Sciences proposes that the dose of Pueraria
mirifica likely to be safe in the Thais, whose
average weight is about 50 kilograms, should
be one not exceeding 50-100 mg/day, given that
human beings are about 5-10 times more sensitive
to toxicity than mice.
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Pueraria Mirifica
